منابع مشابه
The Hows and Ys of Genome Integrity
Much of the Y chromosome consists of large palindromic arrays harboring genes that are critical for spermatogenesis. In this issue, Lange et al. (2009) show that although gene conversion within these arrays maintains their integrity, it also permits rare unequal sister chromatid-exchange events within palindromes that create unstable dicentric chromosomes, resulting in infertility, sex reversal...
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The descriptive term of cerebral palsy encompasses the largest group of childhood movement disorders. Severity and pattern of clinical involvement varies widely dependent on the area of the central nervous system compromised. A multidisciplinary team approach is vital for all the aspects of management to improve function and minimise disability. From a medical viewpoint, there are two pronged a...
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Endoreduplication is a form of nuclear polyploidization that results in multiple, uniform copies of chromosomes. This process is common in plants and animals, especially in tissues with high metabolic activity, and it generally occurs in cells that are terminally differentiated. In plants, endoreduplication is well documented in the endosperm and cotyledons of developing seeds, but it also occu...
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Autoimmune diseases are globally regarded as a consequence of the loss of tolerance against self-antigens. This view has guided our therapeutic efforts to increase the auto-reactive threshold using immunosuppressive drugs. This editorial aims at discussing the strategies to treat autoimmune flares from a different perspective, and in the light of recent molecular insights. At present, the capac...
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Programmed genome rearrangements in ciliates provide fascinating examples of flexible epigenetic genome regulations and important insights into the interaction between transposable elements (TEs) and host genomes. DNA elimination in Tetrahymena thermophila removes approximately 12 000 internal eliminated sequences (IESs), which correspond to one-third of the genome, when the somatic macronucleu...
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ژورنال
عنوان ژورنال: ABEI Journal
سال: 2007
ISSN: 2595-8127,1518-0581
DOI: 10.37389/abei.v9i0.3703